Face the Edge shows how to make a stylized game asset with the Maya, Zbrush, Painter workflow.
Check out this tutorial from the game art outsource Studio Face the Edge that shows how you can create a stylized game asset using a treasure chest as an example.
The Maya, Zbrush, and Painter workflow is a popular one that uses a low polygon model from Maya, a high poly model from Zbrush, and Substance 3D Painter to bring the two together.